Trucker are being targeted by villagers, particularly in the mountainous regions of tge Eastern Cape province for the goods they willbe transporting.
The situation has forced trucking companies to use private security companies to escort trucks.
Police say patrols have been ramped up in hotspots.
The police maintain they can protect deliveries, and say drivers need to alert them to incidents and suspicious behaviour.
If it's your first time driving in the province, make sure you enquire about the hotspots before you get on the road. The looters can pounce at any time of the day.
Video by eNCA