The N3 south bound carriageway is massively backed up from just before Tweedie off ramp near Howick after a tanker transporting sulphuric acid overturned and spilled the acid on the road earlier on Wednesday morning.
According to N3 Toll Concession, the tanker accident happened a few minutes before 10h00.
A Zambian registered truck was involved in the crash.
SA Truckers at the scene told this reporter that the truck was travelling north when it lost control and overturned landing on the south bound lanes.
The tanker got damaged during the crash and spilled the sulphuric acid onto the road.
Emergency services closed the road around 13h00 yo recover the truck and clean out the spillage.
At the time of publishing, around 20h00, the scene had been cleared but traffic on the N3 south bound was backed up to Nottingham road near Mooi River.
Motorists are urged to exercise caution following the reopening of the freeway as the road will be busier than usual.